Association between cardiometabolic index (CMI) and suicidal ideation: A cross-sectional analysis of NHANES 2005 to 2018 data

  • 0Department of Psychiatry, Jiangxi Mental Hospital & Affiliated Mental Hospital of Nanchang University, Nanchang, Jiangxi, China.

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Summary

This summary is machine-generated.

Elevated cardiometabolic index (CMI) is linked to increased suicidal ideation (SI) in US adults. Lifestyle interventions for high CMI may reduce SI risk.

Area Of Science

  • Cardiovascular Health
  • Mental Health Research
  • Metabolic Syndrome

Background

  • Suicide is a leading global cause of death, necessitating identification of modifiable risk factors.
  • Suicidal ideation (SI) is a critical precursor to suicide.
  • Cardiometabolic factors, like the cardiometabolic index (CMI), are increasingly studied for their impact on mental health.

Purpose Of The Study

  • To investigate the correlation between cardiometabolic index (CMI) levels and suicidal ideation (SI) in adult Americans.
  • To analyze data from the National Health and Nutrition Examination Survey (NHANES) spanning 2005-2018.
  • To adjust for demographic, physical, and laboratory factors in assessing the CMI-SI relationship.

Main Methods

  • Utilized NHANES data (2005-2018) from 15,849 adult participants.
  • Conducted multivariate logistic regression analysis to assess the association between CMI and SI.
  • Examined demographic, physical examination, and laboratory data, including lipid profiles.

Main Results

  • A significant positive association was found between CMI and SI (adjusted OR = 1.07, 95% CI: 1.02-1.13, P = .0029).
  • A nonlinear, inverted U-shaped relationship between CMI and SI was identified, with a breakpoint around CMI = 2.08.
  • Consistent findings were observed across various demographic and clinical subgroups.

Conclusions

  • Elevated CMI levels are substantially correlated with increased SI incidence in the US population.
  • Early interventions targeting individuals with high CMI, including lifestyle changes, may help mitigate SI risk.
  • Further research into cardiometabolic health's role in mental well-being is warranted.

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