Related Experiment Video
Updated: May 21, 2025

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
Published on: August 13, 2015
Pain Sensitivity and Depressive Triad Mediate the Relationship Between Trauma and Stress, and Symptoms of
Rachela Antosz-Rekucka1,2, Katarzyna Prochwicz1
1Institute of Psychology, Jagiellonian University in Kraków, Kraków, Poland.
The aim of this study was to test if negative cognitive triad and subjective pain sensitivity mediate the relationship between known risk factors (trauma and stress) and the symptoms of premenstrual disorders (premenstrual syndrome [PMS] and premenstrual dysphoric disorder [PMDD]) measured both retrospectively and prospectively. The study was divided into two stages: a cross-sectional (N = 228) and a prospective diagnosis (N = 90) parts. Correlation and mediation analyses were performed. Both variables mediated the association of trauma and stress with retrospectively measured premenstrual symptoms (mediation between trauma and premenstrual symptoms through depressive triad was full). In the sample of prospectively diagnosed individuals, again, both negative cognitive triad and pain sensitivity mediated the relationship between trauma and PMS/PMDD symptoms partially, and there was full mediation between baseline stress level and premenstrual symptomatology. However, for the mean stress level during the prospective diagnosis phase, only pain sensitivity was a significant, partial mediator. The results suggest that depressive cognitive triad and subjective pain sensitivity may play an important role in the development and maintenance of premenstrual disorders. These findings can contribute to the improvement of PMDD and PMS treatment, emphasising the importance of pain management and addressing core beliefs in psychotherapy of premenstrual disorders.
The aim of this study was to test if negative cognitive triad and subjective pain sensitivity mediate the relationship between known risk factors (trauma and stress) and the symptoms of premenstrual disorders (premenstrual syndrome [PMS] and premenstrual dysphoric disorder [PMDD]) measured both retrospectively and prospectively. The study was divided into two stages: a cross-sectional (N = 228) and a prospective diagnosis (N = 90) parts. Correlation and mediation analyses were performed. Both variables mediated the association of trauma and stress with retrospectively measured premenstrual symptoms (mediation between trauma and premenstrual symptoms through depressive triad was full). In the sample of prospectively diagnosed individuals, again, both negative cognitive triad and pain sensitivity mediated the relationship between trauma and PMS/PMDD symptoms partially, and there was full mediation between baseline stress level and premenstrual symptomatology. However, for the mean stress level during the prospective diagnosis phase, only pain sensitivity was a significant, partial mediator. The results suggest that depressive cognitive triad and subjective pain sensitivity may play an important role in the development and maintenance of premenstrual disorders. These findings can contribute to the improvement of PMDD and PMS treatment, emphasising the importance of pain management and addressing core beliefs in psychotherapy of premenstrual disorders.
Related Concept Videos
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Disorders of the Female Reproductive System
Psychological Responses to Stress
Introduction to Stress and Lifestyle
Panic Disorder

