Primary Cardiac Angiosarcoma Diagnosed by Multimodality Imaging: A Case Report

Area of Science:

• Cardiovascular Imaging
• Oncology
• Radiology

Background:

• Primary cardiac tumors are rare, with malignancy accounting for approximately 10.83%.
• Primary Cardiac Angiosarcoma (PCA) is an exceptionally rare and aggressive malignancy.
• Early and accurate diagnosis is critical for patient management.

Observation:

• A 29-year-old woman presented with chest symptoms, revealing a right atrial mass via ultrasonography and CT.
• Cardiac MRI suggested lymphoma or angiosarcoma; histopathology confirmed cardiac angiosarcoma.
• Initial PET/CT showed high 18F-FDG uptake in the cardiac mass.

Findings:

• Follow-up PET/CT demonstrated increased 18F-FDG uptake and multifocal metastatic nodules in the lungs and mediastinum.
• Multimodality imaging, including PET/CT, revealed extensive disease progression over three months.
• The case illustrates the aggressive nature and metastatic potential of PCA.

Implications:

• Multimodality imaging is vital for precise PCA size and localization assessment.
• Imaging aids in detecting distant metastases and evaluating prognosis in PCA.
• Enhanced understanding of PCA through such cases can improve clinical and radiological diagnosis.