Related Experiment Video
Updated: May 21, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Effect of 0.8mg/ml Losartan on Corneal Opacities
Aisha Fawad1, Waqar Muzaffar2, Unnab Anjum3
1Aisha Fawad, FCPS (Ophth), FRCSGlas (Ophth) Associate Professor of Ophthalmology, Refractive Department, National University of Medical Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Abstract:
Losartan, commonly used as an angiotensin receptor II inhibitor for hypertension, has recently revealed additional therapeutic properties. Studies demonstrate its potential in treating liver fibrosis, mitigating heart disease secondary to radiation, reducing skin scar formation, and even reversing renal cortical fibrosis. In a specific case, a female patient suffering from persistent bilateral nummular keratitis and corneal opacities experienced significant improvement in her left eye after using 0.8mg/ml Losartan eye drops. Untreated right eye showed no change. Based on the positive outcome, patient was offered same treatment in her right eye as well with monthly follow-ups, which she happily accepted. The stark contrast between the treated and untreated eye highlights the promising role of Losartan in treating corneal opacities.
Related Concept Videos
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Drugs: Direct Renin Inhibitors
Heart Failure Drugs: Diuretics

