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Updated: May 21, 2025

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
Published on: July 14, 2023
Knowledge domain and emerging trends in post-stroke cognitive impairment: a bibliometric analysis
Heyu Zhang1, Yanwei Li1, Luqian Zhan2
1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Affiliated With Wenzhou Medical University, Wenzhou, China.
This bibliometric analysis identifies key trends in post-stroke cognitive impairment (PSCI) research, highlighting the significant role of cerebral small vessel disease (CSVD) and its associated factors like hypertension.
Area of Science:
- Neurology
- Geriatrics
- Bibliometrics
Background:
- Post-stroke cognitive impairment (PSCI) is a major cause of disability in the elderly, with stroke being a primary risk factor.
- Cerebral small vessel disease (CSVD) is a significant contributor to stroke and is increasingly recognized for its role in PSCI.
- Early intervention can mitigate PSCI, underscoring the need for research into its underlying mechanisms and risk factors.
Purpose of the Study:
- To identify research priorities and trends in PSCI using bibliometric analysis.
- To explore the specific role of CSVD in the development and progression of PSCI.
- To provide insights for future research and clinical interventions in PSCI.
Main Methods:
- Systematic literature search in the Science Citation Index Expanded (SCI-E) database.
- Bibliometric analysis using VOSviewer and CiteSpace for visualization of research trends and focus.
- Keyword analysis of studies specifically linking CSVD and PSCI.
Main Results:
- A total of 1,943 publications on PSCI were identified, showing a consistent upward trend.
- Key research areas include functional connectivity, systematic reviews, and meta-analyses.
- Hypertension, white matter hyperintensities (WMH), cerebral microbleeds (CMBs), and cerebral amyloid angiopathy (CAA) are prominent keywords in CSVD-related PSCI research.
Conclusions:
- PSCI research is an evolving field with significant growth.
- CSVD, particularly linked to hypertension and MRI markers, plays a crucial role in PSCI.
- This study offers valuable insights for researchers and clinicians focused on PSCI prevention and treatment.
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