Efficacy of ultrasound cyclo-plasty in patients with refractory glaucoma

To assess the efficacy and safety of ultrasound cyclo-plasty (UCP) in lowering intraocular pressure (IOP) among Chinese patients suffering from refractory glaucoma.

In this 12-month retrospective study, 28 patients with refractory glaucoma (IOP≥25 mm Hg) were treated with 8-second UCP using either 8 or 10 probe sectors. The principal measure of efficacy was the decrease in IOP at the following intervals after UCP: 1d, 1, 3, 6, and 12mo, with each measurement compared to baseline.

Mean IOP (in mm Hg) was reduced from 46.8±8.9 to 24.5±3.2, 27.0±4.8, 29.1±4.6, 26.1±4.5, and 28.3±4.8 at 1d, 1, 3, 6, and 12mo postoperatively, respectively. Compared to baseline, IOP reductions at these time points were 45.0%, 39.9%, 35.3%, 41.4%, and 36.7%, respectively. Most patients experienced relief from ocular pain after surgery. No cases of choroidal detachment or hypotony was observed.

UCP is effective in reducing IOP among Chinese patients with refractory glaucoma and shows a favorable safety profile.