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Corey-Fuchs reaction enabled synthesis of natural products: a review
Rabia Ashraf1, Ameer Fawad Zahoor1, Samreen Gul Khan1
1Department of Chemistry, Government College University Faisalabad Faisalabad 38000 Pakistan fawad.zahoor@gcuf.edu.pk.
Abstract:
Natural products can be derived from a vast array of animals, plants and microorganisms and are generally characterized by a wide spectrum of bioactive properties such as anti-viral, anti-cancer, anti-inflammatory and anti-bacterial properties. Synthesis of natural products is of paramount importance in various fields including medicine, biotechnology and agriculture. The Corey-Fuchs reaction, also known as the Ramirez Corey-Fuchs reaction, is a pivotal organic transformation and plays a significant role in the synthesis of intricate natural products and their analogues. This review article highlights the development of the Corey-Fuchs reaction in recent years towards the synthesis of complex natural products including polyketides, alkaloids, terpenoids and peptides.
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