Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebral ischemia with CT.

P Constant1, A M Renou, J M Caillé

  • 1Service Neuro-Radiologie, Centre Jean Abadie, Bordeaux, France.

Computerized Tomography
|January 1, 1977
PubMed
Summary

Computed tomography (CT) effectively tracks changes in the brain after cerebral ischemia. Edema peaks by week two and resolves, while necrosis evolves into cavitation, mirroring cerebrospinal fluid density.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The symbiotic complex of <i>Dendroctonus simplex</i>: implications in the beetle attack and its life cycle.

Bulletin of entomological research·2019
Same author

Editorial. Can and should radiology survive? "Chronicle of a death foretold".

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2010
Same author

Changes in particular glycogen populations of the nerve terminals of Torpedo electric organ stimulated to fatigue in vitro.

Neurochemistry international·2010
Same author

Early macrophage MRI of inflammatory lesions predicts lesion severity and disease development in relapsing EAE.

NeuroImage·2006
Same author

Comparative overview of brain perfusion imaging techniques.

Journal of neuroradiology = Journal de neuroradiologie·2006
Same author

[Commenting comments: to do or not to do?].

Journal of neuroradiology = Journal de neuroradiologie·2004

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Cerebral ischemia, a critical neurological condition, necessitates accurate monitoring of evolving brain tissue damage.
  • Computed tomography (CT) is a key imaging modality for assessing brain injuries, but its precise role in tracking ischemic evolution requires detailed study.

Purpose of the Study:

  • To correlate CT findings with clinical and anatomical outcomes in patients with cerebral ischemia.
  • To elucidate the temporal dynamics of edema and necrosis following ischemic events as visualized by CT.

Main Methods:

  • A cohort of 158 patients diagnosed with cerebral ischemia was studied.
  • Patients were categorized into four clinical groups and underwent CT scans.
  • CT results were cross-referenced with angiography, scintigraphy, and regional cerebral blood flow (rCBF) measurements.

Main Results:

  • CT imaging demonstrated a strong correlation with the clinical and anatomical progression of cerebral ischemia.
  • Cerebral parenchyma density changes were attributed to two distinct processes: edema and necrosis.
  • Edema showed a consistent intensity peak around the second week, resolving before the 20th day post-ischemia.
  • Necrosis varied in initial extent and progressed towards cavitation, resulting in a density akin to cerebrospinal fluid.

Conclusions:

  • CT is a valuable tool for monitoring the evolution of cerebral ischemia, reflecting both clinical and anatomical changes.
  • The distinct patterns of edema and necrosis observed on CT provide insights into the pathophysiology and prognosis of ischemic stroke.

Related Experiment Videos