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Severe Parapneumonic Effusion in a Child With Respiratory Syncytial Virus and Streptococcus pyogenes Coinfection
Hikaru Sugita1, Hiroki Miura1, Kazuhiro Horiba2
1Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, JPN.
Insights
Respiratory syncytial virus (RSV) can precede severe group A Streptococcus infections in children. Rapid deterioration occurred despite antibiotics, highlighting diagnostic challenges with invasive GAS.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Respiratory syncytial virus (RSV) is a common childhood illness.
- Bacterial coinfections can complicate viral respiratory infections.
- Invasive group A Streptococcus (GAS) infections can lead to severe outcomes.
Abstract:
A four-year-old boy with respiratory syncytial virus (RSV) infection and suspected bacterial coinfection deteriorated despite antibiotic treatment. Intensive care and thoracoscopic debridement were required due to parapneumonic effusion. Despite negative pleural fluid cultures, next-generation sequencing detected group A streptococcus (GAS). Even in healthy children without risk factors, RSV infection preceding invasive GAS infection can rapidly deteriorate, making diagnosis difficult.
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