Enzyme-Photocoupled Catalytic Systems Based on Zirconium-Metal-Organic Frameworks

Green, low-carbon, and efficient chemical conversions are crucial for the sustainable development of modern society. Enzyme-photocoupled catalytic systems (EPCS), which mimic natural photosynthesis, utilize solar energy to drive biochemical reactions, providing emergent opportunities to address the limitations of traditional photocatalytic systems. However, the integration and compatibility of photocatalysis and biocatalysis present challenges in designing highly efficient and stable EPCS. Zirconium-based metal-organic frameworks (Zr-MOFs) with outstanding chemical and thermal stability, large surface area, and tunable pore size are ideal candidates for supporting enzymes and enhancing photocatalytic processes. This review aims to integrate Zr-MOFs with EPCS to further promote the development of EPCS. First, an overview of the basic components and design principles of EPCS is provided, highlighting the importance of the unique properties of Zr-MOFs. After that, three different strategies for combining enzymes with Zr-MOFs are summarized and their respective advantages are evaluated. Finally, the development opportunities and some problems to be solved in this field are proposed.