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Published on: February 23, 2014
Joint consensus on reducing the burden of invasive meningococcal disease in the Asia-Pacific region
Gang Liu1, Maria Liza Antoinette M Gonzales2, Wai Hung Chan3
1Department of Infectious Diseases, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, National Center for Children's Health, Beijing, China.
Abstract:
Invasive meningococcal disease (IMD) imposes a heavy burden of mortality and life-long sequelae on infected individuals and has devastating impacts on their family members. International data show that meningococcal vaccination programs have reduced IMD incidence and changed the serogroup distribution of the disease. Furthermore, newer data show that although the public health measures in response to the coronavirus disease 2019 (COVID-19) pandemic temporarily reduced the incidence of IMD, there has been a resurgence in the years since. In the Asia-Pacific (APAC) region, many countries do not include meningococcal vaccines in their routine vaccination programs, and approaches to IMD surveillance are inconsistent. This review summarizes recent data and consensus statements from a group of experts from selected APAC countries on the burden of IMD in the region, evidence for vaccination, and how barriers to IMD vaccination may be addressed.
Insights
Meningococcal vaccination programs effectively reduce invasive meningococcal disease (IMD) globally. This review examines IMD burden, vaccination evidence, and barriers in the Asia-Pacific region.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Invasive meningococcal disease (IMD) causes significant mortality and long-term disability.
- Global vaccination programs have successfully reduced IMD incidence and altered serogroup prevalence.
- The COVID-19 pandemic temporarily decreased IMD rates, followed by a resurgence.
Purpose of the Study:
- To review the current burden of IMD in the Asia-Pacific (APAC) region.
- To evaluate the evidence supporting meningococcal vaccination strategies.
- To identify and propose solutions for barriers to IMD vaccination in APAC.
Main Methods:
- Expert consensus review of recent data.
- Analysis of international and regional IMD surveillance data.
- Summary of current meningococcal vaccine efficacy and impact.
Main Results:
- Many APAC countries lack routine meningococcal vaccination programs.
- IMD surveillance methods are inconsistent across the APAC region.
- Evidence supports the role of vaccination in controlling IMD.
Conclusions:
- Addressing barriers is crucial to improve meningococcal vaccine uptake in APAC.
- Enhanced surveillance and standardized vaccination programs are needed.
- Vaccination remains a key strategy to reduce the burden of IMD in the APAC region.
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