Joint consensus on reducing the burden of invasive meningococcal disease in the Asia-Pacific region

Gang Liu1, Maria Liza Antoinette M Gonzales2, Wai Hung Chan3

  • 1Department of Infectious Diseases, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, National Center for Children's Health, Beijing, China.

Insights

Meningococcal vaccination programs effectively reduce invasive meningococcal disease (IMD) globally. This review examines IMD burden, vaccination evidence, and barriers in the Asia-Pacific region.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Vaccinology

Background:

  • Invasive meningococcal disease (IMD) causes significant mortality and long-term disability.
  • Global vaccination programs have successfully reduced IMD incidence and altered serogroup prevalence.
  • The COVID-19 pandemic temporarily decreased IMD rates, followed by a resurgence.

Purpose of the Study:

  • To review the current burden of IMD in the Asia-Pacific (APAC) region.
  • To evaluate the evidence supporting meningococcal vaccination strategies.
  • To identify and propose solutions for barriers to IMD vaccination in APAC.

Main Methods:

  • Expert consensus review of recent data.
  • Analysis of international and regional IMD surveillance data.
  • Summary of current meningococcal vaccine efficacy and impact.

Main Results:

  • Many APAC countries lack routine meningococcal vaccination programs.
  • IMD surveillance methods are inconsistent across the APAC region.
  • Evidence supports the role of vaccination in controlling IMD.

Conclusions:

  • Addressing barriers is crucial to improve meningococcal vaccine uptake in APAC.
  • Enhanced surveillance and standardized vaccination programs are needed.
  • Vaccination remains a key strategy to reduce the burden of IMD in the APAC region.

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