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Updated: Jun 21, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Effect of precursors on carbon dot functionalization and applications: a review
Sara Strickland1, Luke Fourroux1, Dimitri Pappas1
1Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA. D.pappas@ttu.edu.
Abstract:
Carbon dots (CDs) are a type of carbon-based nanoparticle (NP) that have risen in popularity due to their unique tuneable physicochemical and optical properties. CDs have received a significant amount of attention in biological based applications due to their low cytotoxicity, stable photoluminescence, and small size. They have demonstrated the ability to retain certain properties from their carbon precursors, enabling NP design via precursor selection. Thus, direct functionalization of a CD can be achieved without the need for post synthesis modification. However, CDs derived from the same class of carbon precursor can also have profoundly variable applications. Indicating that, in conjunction with precursor properties, other functional attributes can be imposed on the CD during the synthesis process to enable cross-cutting applications from a single carbon precursor. Here, we will highlight various CD precursors and the resulting multifunctional CDs, as well as rational design of CDs for specific biological and materials science applications via precursor selection.
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