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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Aortic calcium score predicts early outcomes in aortoiliac revascularization
Adalberto Batalha Megale1, Nelson Wolosker1, Vitoria Magliari Kalil1
1Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Insights
Lower limb artery calcium scores predict outcomes in critical limb ischemia patients. Below-knee artery calcification indicates long-term revascularization and amputation risk, while aortic calcification predicts short-term events.
Area of Science:
- Vascular Surgery
- Radiology
- Cardiovascular Medicine
Background:
- Critical limb ischemia (CLI) poses significant risks after aortoiliac revascularization.
- Aortic and lower limb artery calcification are increasingly recognized as important factors in vascular disease.
- Computed tomography angiography (CTA) allows for detailed assessment of arterial calcification.
Purpose of the Study:
- To investigate the association between preoperative lower limb artery calcium scores and clinical outcomes in patients with CLI undergoing aortoiliac revascularization.
- To determine if CTA-derived calcium scores can predict short-term and long-term adverse events.
Main Methods:
- Retrospective review of 14 interventions in 11 patients with CLI.
- Calculation of calcium scores in the aorta, iliac, femoropopliteal, and below-knee arteries using CTA.
- Evaluation of outcomes including amputation, patency, death, revascularization, readmission, and major adverse limb events (MALEs) over a 12-month follow-up period.
Main Results:
- Higher aortic calcium scores correlated with 30-day amputation and subsequent revascularization.
- Elevated below-knee artery calcium scores were associated with 12-month amputation, revascularization, readmissions, and MALEs.
- Below-knee artery calcium scores predicted MALEs at both 30 days and 1 year.
Conclusions:
- Below-knee artery calcium score is a significant predictor of long-term adverse outcomes, including revascularization, amputation, readmission, and MALEs.
- Aortic calcium score is a valuable marker for predicting short-term (30-day) amputation and revascularization after aortoiliac procedures.
Background:
Calcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months. ■ The calcium score can be calculated using computed tomography angiography. ■ The aortic calcium score was associated with amputation and subsequent revascularization within 30 days. ■ The calcium score in below-the-knee arteries was higher in the patients who underwent subsequent revascularization and amputation at 12 months.
Objective:
To evaluate the association between lower limb artery calcium scores in preoperative computed tomography angiography and outcomes of patients with critical limb ischemia who underwent revascularization procedures in the aortoiliac segment.
Methods:
We retrospectively reviewed 14 interventions performed on 11 patients. The calcium score was calculated in segments of the aorta, iliac, femoropopliteal, and below-the-knee arteries. The evaluated outcomes included amputation, patency, death, subsequent revascularization, and readmission. Major adverse limb events were defined as amputation, subsequent revascularization, or readmission. The patients were followed through a 12-month period.
Results:
Higher aortic calcium scores were associated with amputation within 30 days (5,767.6 versus 805.3; p=0.02). Amputation during the first year correlated with a higher below-the-knee arteries calcium score (672.4 versus 163.25; p=0.04). Subsequent revascularization within 30 days was associated with a higher aortic calcium score (3,686.8 versus 645.2; p=0.008), while below-the-knee arteries calcium scores were associated with revascularization within 30 days (155.5 versus 817; p=0.05) and 12 months (158.875 versus 679.4; p=0.019). Readmissions within 1 year were more prevalent with higher below-the-knee arteries calcium scores (882.4 versus 32; p=0.011). Major adverse limb events were related to below-the-knee arteries calcium scores at 30 days (158.875 versus 679.4; p=0.019) and 1 year (12.3 versus 910.1; p=0.002).
Conclusion:
Below-the-knee arteries calcium score is a predictor of long-term revascularization, amputation, readmission, and major adverse limb events. The aortic calcium score was associated with amputation and subsequent revascularization within the first 30 days.
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