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Updated: May 21, 2025
08:46
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Fertility Preservation in People With Cancer: ASCO Guideline Update.
H Irene Su1, Christina Lacchetti2, Joseph Letourneau3
1University of California, San Diego, San Diego, CA.
Summary
Cancer patients need timely fertility preservation (FP) counseling and options. Recommendations cover sperm, egg, and ovarian tissue cryopreservation, emphasizing discussion before treatment and access to specialists.
Area of Science:
- Oncology
- Reproductive Medicine
- Medical Ethics
Background:
- Cancer diagnosis necessitates discussion of reproductive risks and fertility preservation (FP).
- Evolving FP techniques require updated clinical guidelines for cancer patients.
Purpose of the Study:
- To provide updated, evidence-based fertility preservation recommendations for individuals with cancer.
- To guide clinicians in counseling and offering FP options to cancer patients.
Main Methods:
- Systematic review of 166 studies.
- Convening of a multidisciplinary Expert Panel to update recommendations.
Main Results:
- Sperm cryopreservation is recommended for males before cancer treatment.
- Established FP methods for females include embryo, oocyte, and ovarian tissue cryopreservation.
- Ovarian tissue cryopreservation is the only established FP method for prepubertal females.
Conclusions:
- Cancer patients should be evaluated for reproductive risks at diagnosis and during survivorship.
- Referral to reproductive specialists is crucial for patients considering FP.
- Oncology teams must ensure prompt access to FP services and advocate for coverage.
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