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Updated: May 21, 2025

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
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A supported lipid bilayer to model solid-ordered membrane domains

Sally Helmy1, Paola Brocca2, Alexandros Koutsioubas3

  • 1Department of Medical Biotechnology and Translational Medicine, Università Degli Studi di Milano, Milano, Italy; Biophysics Group, Physics Department, Faculty of Science, Ain Shams University, Cairo, Egypt.

Journal of Colloid and Interface Science
|March 19, 2025
PubMed
Summary

Researchers developed a new three-component membrane model using DMPC, sphingomyelin, and cholesterol to mimic lipid rafts. This model allows for studying membrane organization and physical properties relevant to cellular functions.

Keywords:
Atomic force microscopyCholesterolDMPCDifferential scanning calorimetryLipid membraneNeutron reflectometrySphingomyelin

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