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Predictors of poor outcome in the acute phase after a first-ever stroke in a population-based study in Matão, Brazil

Cesar Minelli1,2, Esther Maria Langhi Chiozzini2, Liliana Tiene Ujikawa2

  • 1Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.

Arquivos De Neuro-Psiquiatria
|March 19, 2025
PubMed

Insights

Predictors like older age, female gender, and stroke severity indicate a poor prognosis for first-ever stroke (FES) patients in middle-income countries. Early interventions are crucial for improving outcomes.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • Limited data exists on stroke outcome predictors in middle-income countries.
  • Understanding these predictors is vital for targeted interventions.

Purpose of the Study:

  • To identify predictors of poor outcomes within 3 months and 1 year post-first-ever stroke (FES).
  • To analyze these predictors in a population-based study in Brazil.

Main Methods:

  • Prospective investigation of FES patients in Matão, Brazil (2015-2020).
  • Poor outcome defined as modified Rankin scale (mRS) score 3-6 at 3 months and 1 year.
  • Logistic regression analysis to identify associated predictors.

Main Results:

  • 50.4% and 47.1% of patients had poor outcomes at 3 months and 1 year, respectively.
  • Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities were significant predictors.
  • Analysis included 378 patients from an initial 783.

Conclusions:

  • Both non-modifiable and modifiable predictors impact FES prognosis in middle-income settings.
  • Interventions targeting high-risk populations and improving acute stroke care are necessary.
Abstract

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