Related Experiment Video
Updated: May 21, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 2. General Practices
Published on: October 3, 2016
The first reported case of monkeypox virus clade Ⅰb infection in china-clinical presentation and epidemiologic
Weizhe Pan1, Rui Ge1, Guoying Zhu1
1Jiaxing Center for Disease Control and Prevention, Jiaxing, China.
Abstract:
Recently, Monkeypox Virus (MPXV) clade Ib has caused serious health hazards in several countries. Herein, we report the first case of a clade Ib MPXV infection in China. MPXV was detected in a 28-year-old female on January 2, 2025. Whole-genome sequencing analysis revealed the strain to be clade Ib. The case presented with headache and disseminated rashes, with symptoms resolving symptomatic treatment and scabs shedding prior to discharge. Epidemiological studies and laboratory tests suggested transmission through close contact with a man who recently came from the Democratic Republic of Congo. Significantly, although some environmental samples tested positive, all contacts reminded negative, indicating that absence of secondary transmission. Furthermore, the clinical presentation of this case showed different manifestations from clade IIb MPXV infections. Epidemiological patterns also suggested sexual transmission served as the predominant route for clade Ib MPXV spread. These findings provide critical insights to enhance early detection strategies and inform targeted intervention measures aimed at curbing disease progression while mitigating risks of wider community spread.
More Related Videos
08:10Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
Published on: May 2, 2019
10:11Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Related Concept Videos
Viral Mutations
Viral Recombination
Cross-reactivity
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories: