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Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

52.1K
Overview
52.1K
  1. Home
  3. Research Domains
  5. Agricultural, Veterinary And Food Sciences
  7. Veterinary Sciences
  9. Veterinary Medicine (excl. Urology)
  11. Multidrug-resistant Uropathogens In Companion Animals: A Comprehensive Study From Clinical Cases And A Genomic Analysis Of A Ctx-m-14-producing Escherichia Coli St354, A Leading Cause Of Urinary Tract Infections

Multidrug-Resistant Uropathogens in Companion Animals: A Comprehensive Study from Clinical Cases and a Genomic Analysis of a CTX-M-14-Producing Escherichia coli ST354, a Leading Cause of Urinary Tract Infections

Victoria T S Sakauchi1, Bianca C T Silva1, Amanda Haisi2

  • 1Laboratory of Bacterial Zoonosis, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.

Microbial Drug Resistance (Larchmont, N.Y.)
|March 19, 2025

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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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Establishment and Characterization of UTI and CAUTI in a Mouse Model
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Establishment and Characterization of UTI and CAUTI in a Mouse Model

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View abstract on PubMed

Summary
This summary is machine-generated.

This study identified common bacteria causing urinary tract infections (UTIs) in pets in Brazil, finding high rates of antibiotic resistance, particularly in Escherichia coli. Findings highlight the need for better antibiotic stewardship in veterinary medicine.

Area of Science:

  • Veterinary Medicine
  • Microbiology
  • One Health

Background:

  • Urinary tract infections (UTIs) present significant clinical challenges in small animals due to recurrence and discomfort.
  • Understanding causative agents and antimicrobial resistance (AMR) is crucial for effective treatment.

Purpose of the Study:

  • To investigate bacterial pathogens and AMR patterns in canine and feline UTIs.
  • To identify specific high-risk strains and their genetic relatedness.

Main Methods:

  • Bacterial culture and identification using MALDI-TOF MS from cystocentesis samples.
  • Antimicrobial susceptibility testing via Kirby-Bauer method.
  • Whole-genome sequencing and phylogenetic analysis of a key uropathogenic Escherichia coli strain.
Keywords:
One Healthcystitisgenomic analysissmall animals

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Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
09:44

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Published on: December 23, 2022

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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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Establishment and Characterization of UTI and CAUTI in a Mouse Model
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Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

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Main Results:

  • Escherichia coli was the most prevalent pathogen (27.9%), followed by Staphylococcus pseudintermedius, Proteus mirabilis, and Klebsiella pneumoniae.
  • High ampicillin resistance (70.4%) was noted in enterobacteria, with frequent multidrug resistance in E. coli.
  • A feline E. coli ST354 strain producing CTX-M-14 extended-spectrum beta-lactamase showed genetic links to environmental and poultry sources in Brazil.

Conclusions:

  • Veterinary UTIs in Brazil are caused by common pathogens with significant AMR.
  • The presence of globally relevant resistant strains like ST354 underscores the importance of AMR surveillance.
  • Enhanced antibiotic stewardship and a One Health approach are essential for managing veterinary UTIs.
surveillance