Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

K Barry Sharpless1, M G Finn2, Hartmuth C Kolb3,4

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

Angewandte Chemie (International Ed. in English)
|March 20, 2025
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of chemical features for improved outer membrane permeation in mycobacteria using machine learning.

Nature microbiology·2026
Same author

Tau positron emission tomography analysis methods for the quantification of tau spread in preclinical and early Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Preclinical Evaluation of [<sup>18</sup>F]JNJ-1: A Novel Positron Emission Tomography Ligand Targeting AMPAR/TARP γ8.

Molecular imaging and biology·2026
Same author

Liquid-Phase CO<b><sub>2</sub></b> Capture by a Nonaqueous Cooperative Absorption Mechanism.

Journal of the American Chemical Society·2026
Same author

Characterization Standard for <i>In-situ</i> Cryo-electron Tomography.

bioRxiv : the preprint server for biology·2026
Same author

Orthogonal Chemistry Enables Precision Nanoparticle Cofunctionalization for Tuning Immune Stimulation and Antigen Presentation.

Biomacromolecules·2026
Same journal

A Domino-Synthesized Dicoordinate Copper(I) Bis-imidazopyridine Complex Triggering Cuproptosis/Ferroptosis for Enhanced Cancer Immunotherapy.

Angewandte Chemie (International ed. in English)·2026
Same journal

Mirror-Symmetric Organic Two-Dimensional Crystals for Alternative Photon Transport Pathways.

Angewandte Chemie (International ed. in English)·2026
Same journal

Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki-Hiyama-Kishi Coupling.

Angewandte Chemie (International ed. in English)·2026
Same journal

Facile Synthesis of α,ω-Dihydroxy Telechelic Macromonomers From Ethylene and α-Olefins for Recyclable Alternating Block Copolymers.

Angewandte Chemie (International ed. in English)·2026
Same journal

Multi-Atom Sub-Nanometer Assemblies on Interpenetrating Multi-Chambered N/C Nanospheres.

Angewandte Chemie (International ed. in English)·2026
Same journal

A Synergistic C<sub>2+</sub> Alcohols/Olefins-Intermediated Pathway Boosts CO<sub>2</sub> Hydrogenation to Aromatics.

Angewandte Chemie (International ed. in English)·2026
See all related articles

Click chemistry has revealed that perfect chemical reactions are possible. This groundbreaking discovery in bond-making and bond-breaking reactions promises to revolutionize chemistry and its benefits for humanity.

Area of Science:

  • Organic Chemistry
  • Chemical Synthesis

Context:

  • Click chemistry represents a paradigm shift in chemical synthesis.
  • The concept focuses on reactions that are high-yielding, selective, and simple to perform.

Purpose:

  • To highlight the significance of "perfect reactions" enabled by click chemistry.
  • To underscore the transformative potential of this realization in the field of chemistry.

Summary:

  • The core achievement of click chemistry is the demonstration that ideal chemical reactions, characterized by efficiency and predictability, can be attained.
  • This challenges traditional notions of chemical reactivity and opens new avenues for molecular construction.

Impact:

  • The advent of perfect reactions is poised to fundamentally alter the practice of chemistry.

Related Experiment Videos

  • This advancement promises to accelerate the development of new materials, medicines, and technologies, ultimately benefiting humankind.