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K Barry Sharpless1, M G Finn2, Hartmuth C Kolb3,4
1Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
Angewandte Chemie (International Ed. in English)
|March 20, 2025
Abstract:
The click chemist's playground: The most important certainty-of-chance outcome of click chemistry was the realization that perfect reactions can exist. Chemistry is about bond-making and bond-breaking reactions between atoms and molecules. So, the emergence of "perfect reaction" status promises to be transformative to the very heart of chemistry, and thence to the range of benefits for mankind that its future evolution may hold.