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Updated: Jun 16, 2025

Lensless Fluorescent Microscopy on a Chip
Published on: August 17, 2011
Glass slide evanescent wave fluorescence biosensor integrated coupling aspherical lens with a sensing range of over
Qun Dai1, Yanjun Hu1, Xingang Dai1
1Key Laboratory of All Optical Network and Advanced Telecommunication Network, Ministry of Education, Institute of Lightwave Technology, Beijing Jiaotong University, Beijing, China.
Abstract:
Evanescent wave fluorescence biosensor is a research hotspot in the field of biomedical detection due to high sensitivity and specificity. However, the fluorescence biosensor still shows small sensing range and high production cost. In this paper, a simple and cheap sub-millimetre thickness glass slide evanescent wave fluorescence biosensor integrated an aspherical coupling lens is proposed. The proposed sub-millimetre thickness glass slide fluorescence biosensor shows a sensing range of over 20 mm for multi-wavelength operation for the three materials of N-BK7, N-LAF21 and N-LASF41. This will be helpful for the evanescent wave fluorescence biosensor.
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