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Related Experiment Video

Updated: May 1, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
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ECT-induced primary open-angle glaucoma in a patient with unstable thyroid function: a case report.

Cuiyuan Fu1,2, Xiuzhen Yang1, Kun Li1,2

  • 1Department of Physical Therapy, Shandong Daizhuang Hospital, Jining, China.

Frontiers in Psychiatry
|March 20, 2025
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Summary
This summary is machine-generated.

Electroconvulsive therapy (ECT) may pose risks for patients with schizophrenia and unstable thyroid function. Monitoring intraocular pressure during ECT is crucial to prevent glaucoma complications in these vulnerable individuals.

Keywords:
GlaucomaHyperthyroidismSchizophreniaeffectivityelectroconvulsive therapysafety

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Area of Science:

  • Psychiatry
  • Ophthalmology
  • Endocrinology

Background:

  • Schizophrenia is a severe psychiatric disorder often treated with electroconvulsive therapy (ECT).
  • ECT can transiently increase intraocular pressure (IOP).
  • The ophthalmic risks of ECT in patients with coexisting hyperthyroidism are not well-documented.

Observation:

  • A case report details an elderly woman with schizophrenia and unstable hyperthyroidism who developed primary open-angle glaucoma after three ECT sessions.
  • The patient had no prior history of glaucoma.
  • Her intraocular pressure normalized spontaneously after the fourth ECT session.

Findings:

  • The patient's intraocular pressure normalized before and after the fourth ECT session.
  • No further ocular discomfort was reported during subsequent ECT sessions.
  • This case highlights a potential link between ECT, unstable thyroid function, and new-onset glaucoma.

Implications:

  • This case underscores the importance of monitoring intraocular pressure in patients with unstable thyroid function undergoing ECT.
  • Proactive ophthalmic monitoring may help mitigate the risk of glaucoma development or exacerbation.
  • Further research is needed to elucidate the specific risks and management strategies for this patient population.