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Non-occlusive Mesenteric Ischemia Following Severe Traumatic Brain Injury: A Case Report
Kazuki Fujii1, Kiyoshi Takemoto1, Shiho Yoshida1
1Emergency and Critical Care Medicine, Nara Prefecture General Medical Center, Nara, JPN.
Cureus
|March 20, 2025
Summary
Severe traumatic brain injury (sTBI) may be a risk factor for non-occlusive mesenteric ischemia (NOMI). This case report highlights a potential link between sTBI and NOMI development, suggesting further investigation into this association.
Area of Science:
- Neuroscience
- Gastroenterology
- Critical Care Medicine
Background:
- Non-occlusive mesenteric ischemia (NOMI) is a serious condition with several known risk factors.
- The association between severe traumatic brain injury (sTBI) and NOMI has not been previously reported.
Observation:
- A young woman with no prior risk factors developed NOMI following sTBI.
- The patient experienced sudden cardiac arrest on postoperative day 14, attributed to aspiration.
- Aspiration was linked to abdominal distension and vomiting secondary to NOMI.
Findings:
- This case presents the first reported instance of NOMI in a patient with sTBI as the sole apparent risk factor.
- The clinical course suggests a potential causal relationship between sTBI and the subsequent development of NOMI.
Implications:
- Severe traumatic brain injury may represent a novel risk factor for non-occlusive mesenteric ischemia.
- Clinicians should consider NOMI in patients with sTBI, particularly those presenting with gastrointestinal complications.
- Further research is warranted to elucidate the pathophysiological mechanisms linking sTBI and NOMI.
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