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Updated: May 21, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Effects of suggestion therapy on mood and sleep quality in middle-aged women with depression
Yuan Jiang1, Ke-Ke Xia1, Zhi-Yuan Lin2
1Department of Psychiatry, The Seventh People's Hospital of Wenzhou, Wenzhou 325000, Zhejiang Province, China.
Background:
Depression is one of the most common mental disorders, with high rates of disability, particularly among women.
Aim:
To explore the effects of suggestion therapy on anxiety, mood, and sleep-quality in middle-aged women with depression treated with escitalopram.
Methods:
Overall, 102 female patients with depression aged 35-49 years were divided into control and experimental groups. The control group received oral escitalopram therapy, starting at a dose of 5 mg/day, which was gradually increased to 10-20 mg/day after 1 week for a total of 8 weeks. The experimental group received the suggested therapy based on the control group. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Profile of Mood States-Short Form, and Pittsburgh Sleep Quality Index (PSQI) were used to assess depression, anxiety, mood status, and sleep quality.
Results:
Before treatment, there were no significant differences in the SDS, SAS, Profile of Mood States, and PSQI scores between the two groups (P > 0.05). After treatment, compared to the control group and baseline, the SDS, SAS, tension-anxiety, depression-dejection, and confusion-bewilderment scores in the experimental group significantly decreased (P < 0.05), whereas sleep efficiency, sleep disturbance, hypnotics, and PSQI scores significantly increased (P < 0.05).
Conclusion:
Suggestion therapy combined with escitalopram treatment can reduce the severity of depression and anxiety, change mood status, and improve sleep quality in middle-aged women with depression.
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