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Metaplastic breast carcinoma: a rare and aggressive entity
Manar Zaiter1, Jessica Naccour2, Faten Khalil3
1Department of Radiology, MEIH, Bsalim, Lebanon.
Annals of Medicine and Surgery (2012)
|March 20, 2025
Summary
Metaplastic breast carcinoma (MpBC) is a rare, aggressive breast cancer subtype. Despite diagnostic challenges, survival outcomes for MpBC may be comparable to aggressive invasive ductal carcinoma (IDC) with tailored treatments.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Breast cancer (BC) is the most common malignancy in women, with invasive ductal carcinoma (IDC) being the most frequent subtype.
- Metaplastic breast carcinoma (MpBC) is a rare (<2% of cases), aggressive BC subtype with heterogeneous characteristics and poorer prognosis.
- MpBC presents diagnostic and therapeutic challenges due to its aggressive nature and difficulty in differentiating from other breast tumors via standard imaging.
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