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The digital dialogue on premature ejaculation: evaluating the efficacy of artificial intelligence-driven responses
Hakan Anıl1, Mehmet Vehbi Kayra2
1Department of Urology, Faculty of Medicine, Istanbul Aydin University, Beşyol, İnönü Street. No: 38, Küçükçekmece, 34295, Istanbul, Turkey. hakananil@aydin.edu.tr.
International Urology and Nephrology
|March 20, 2025
Summary
AI chatbots like Llama and Gemini provide higher quality health information on premature ejaculation (PME) than ChatGPT, though readability is similar across all models. Llama scored highest in overall quality assessments.
Area of Science:
- Artificial Intelligence in Healthcare
- Digital Health Information Quality
- Medical Natural Language Processing
Background:
- The proliferation of AI chatbots presents new avenues for health information dissemination.
- Premature ejaculation (PME) is a common sexual health concern requiring reliable information.
- Evaluating the quality of AI-generated health content is crucial for patient safety and trust.
Purpose of the Study:
- To assess and compare the quality and comprehensibility of responses from ChatGPT, Gemini, and Llama regarding premature ejaculation (PME).
- To determine which AI chatbot provides the most accurate, clear, and trustworthy information on PME.
Main Methods:
- 25 frequently asked questions (FAQs) on PME were sourced using Google Trends and Semrush.
- Responses from ChatGPT, Gemini, and Llama were analyzed using Flesch Reading Ease (FRES), Flesch-Kincaid Grade Level (FKGL), modified DISCERN (mDISCERN), and Ensuring Quality Information for Patients (EQIP) scores.
- Statistical analysis was performed to compare readability and quality metrics across the chatbots.
Main Results:
- Readability scores (FRES, FKGL) were comparable across all three AI models.
- Llama demonstrated the highest mean EQIP scores (72.2 ± 1.1), followed by Gemini (67.6 ± 4.5) and ChatGPT (63.1 ± 4.9).
- Llama and Gemini achieved higher median mDISCERN scores (3) compared to ChatGPT (2), indicating superior information quality.
Conclusions:
- AI chatbots exhibit similar readability levels when discussing premature ejaculation.
- Llama and Gemini offer superior quality and trustworthiness in their responses on PME compared to ChatGPT, based on EQIP and mDISCERN evaluations.
- Further research is needed to optimize AI-generated health information for accuracy and patient comprehension.

