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Updated: May 21, 2025

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
[Study on effectiveness of multicomponent exercise interventions for healthy aging]
1Department of Sports Science, College of Education, Zhejiang University, Hangzhou 310058, China.
Abstract:
Objective: To analyze the effectiveness of multicomponent exercise (ME) in old adults, and provide reference for the promotion of healthy aging. Methods: Literature on ME intervention for old adults published until February 29, 2024 were retrieved from Web of Science, PubMed, Scopus, Embase, EBSCO, Cochrane Library, CNKI, Wanfang Data, and VIP Database. After screening and evaluation, an umbrella review was conducted. Results: In total, 15 systematic reviews and Meta-analyzes (193 randomized controlled trials and 19 203 participants) were included. The umbrella review suggested that the average standardized mean difference (SMD) affecting physical function/health of ME was between 0.40 and 1.00, the average SMD affecting brain health was between -0.30 and 1.60, the average SMD affecting mood/mental health was between 0.01 and 0.20, and the average SMD affecting quality of life was between -0.20 and 0.40. Effects of ME on lower limb strength [mean difference (MD)=1.1] and aerobic capacity (MD=0.8) were better compared with general strength exercise and aerobic exercise respectively. Effects of ME on cognitive function (MD=0.99) were better compared with strength exercise (MD=0.84), aerobic exercise (MD=0.77), and mind-body exercise (MD=0.63). Effects of ME on executive function (MD=0.72) were better compared with aerobic exercise (MD=0.62), strength exercise (MD=0.44), and mind-body exercise (MD=0.36). Effects of ME on activity of daily living (SMD=0.32) were better compared with strength exercise (SMD=0.12). Conclusions: ME can clearly improve the physical function/health and brain health in old adults. The impact varies with different participants, exercise program designs, and assessment methods. However, its effect on mood/mental health and the quality of life still need further verification. ME might show better effects compared with general single component exercise (such as strength exercise, aerobic exercise) and mind-body exercise in improving lower limb strength, aerobic capacity, cognitive function, executive function, and activity of daily living in specific elderly populations. Given the impact of the quantity, quality and heterogeneity of the reviews included, the conclusions mentioned above still need validation in practice.
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