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Updated: May 21, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

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Foxp3+CD8+ regulatory T cells: bona fide Tregs with cytotoxic function

Shunqun Luo1, Jemma H Larson2, Bruce R Blazar2

  • 1Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201.

Trends in Immunology
|March 20, 2025
PubMed

Keywords:
CD8 regulatory T cellscytotoxic functioninduction determinantssuppressive function

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