Related Experiment Video
Updated: May 21, 2025

The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury
Published on: October 21, 2017
Insight into the lifestyle of young people with chronic liver disease
Mohamed Ali1,2, Sowmiya Gunabalasingam1, Jemma Day1
1Young Adult Liver Service, King's College Hospital NHS Foundation Trust, London, UK.
Abstract:
The impact of chronic liver disease (CLD) in young people on lifestyle is poorly explored. One hundred four young people (20.51 years, male 44%), including 37% with autoimmune liver disease and 19% post-liver transplantation, completed an anonymous health questionnaire Thirty-nine per cent were considered overweight/obese. Female body mass index (BMI) was higher than male BMI (26.5 vs. 23.4, p = 0.018), and those taking steroids (n = 38) were more likely to be overweight/obese (66% vs. 31%, p = 0.03). Half of the cohort reported 'never' to drink alcohol and 19% had taken recreational drugs with 5% mentioning regular use of alcohol and recreational drugs each. Menstrual dysregulation was common including oligomenorrhoea (31%) and irregular periods (25%). The prevalence of overweight/obese status in young people with CLD is worrying, with females and those on steroid treatment most affected. Whereas alcohol consumption is less common compared to peers, the use of recreational drugs in this population warrants further attention.
More Related Videos
10:25"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
09:27Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
Published on: April 1, 2021
Related Concept Videos
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Liver Physiology
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...