Prognostic value of the neutrophil‑to‑lymphocyte ratio in renal cell carcinoma: A systematic review and meta‑analysis

  • 0Department of Urology, Lanxi People's Hospital, Jinhua, Zhejiang 321100, P.R. China.

|

|

Summary

This summary is machine-generated.

The neutrophil-to-lymphocyte ratio (NLR) can predict outcomes in renal cell carcinoma (RCC) patients. Elevated NLR levels are linked to a poorer prognosis, highlighting its role as an independent prognostic indicator.

Area Of Science

  • Oncology
  • Immunology

Background

  • The neutrophil-to-lymphocyte ratio (NLR) reflects systemic inflammation and tumor microenvironment status.
  • NLR may correlate with tumor aggressiveness and patient prognosis in various cancers.

Purpose Of The Study

  • To systematically review and meta-analyze the impact of NLR on the prognosis of renal cell carcinoma (RCC) patients.

Main Methods

  • Comprehensive literature search of PubMed, Embase, and Cochrane Library.
  • Rigorous literature screening and quality assessment.
  • Systematic quantitative analysis (meta-analysis) of eligible studies.

Main Results

  • A significant association was found between elevated NLR levels and poor prognosis in RCC patients.
  • High NLR levels may serve as an independent predictor of unfavorable outcomes in RCC.

Conclusions

  • NLR is a valuable and independent prognostic indicator for patients with renal cell carcinoma.
  • Findings support the use of NLR in clinical decision-making for RCC patient management and treatment strategies.