Prognostic value of the neutrophil‑to‑lymphocyte ratio in renal cell carcinoma: A systematic review and meta‑analysis
- Kecheng Lou 1, Xin Cheng 2
- Kecheng Lou 1, Xin Cheng 2
- 1Department of Urology, Lanxi People's Hospital, Jinhua, Zhejiang 321100, P.R. China.
- 2Department of Urology, Ganzhou Cancer Hospital of Gannan Medical University, Ganzhou, Jiangxi 341000, P.R. China.
- 0Department of Urology, Lanxi People's Hospital, Jinhua, Zhejiang 321100, P.R. China.
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View abstract on PubMed
Summary
This summary is machine-generated.The neutrophil-to-lymphocyte ratio (NLR) can predict outcomes in renal cell carcinoma (RCC) patients. Elevated NLR levels are linked to a poorer prognosis, highlighting its role as an independent prognostic indicator.
Area Of Science
- Oncology
- Immunology
Background
- The neutrophil-to-lymphocyte ratio (NLR) reflects systemic inflammation and tumor microenvironment status.
- NLR may correlate with tumor aggressiveness and patient prognosis in various cancers.
Purpose Of The Study
- To systematically review and meta-analyze the impact of NLR on the prognosis of renal cell carcinoma (RCC) patients.
Main Methods
- Comprehensive literature search of PubMed, Embase, and Cochrane Library.
- Rigorous literature screening and quality assessment.
- Systematic quantitative analysis (meta-analysis) of eligible studies.
Main Results
- A significant association was found between elevated NLR levels and poor prognosis in RCC patients.
- High NLR levels may serve as an independent predictor of unfavorable outcomes in RCC.
Conclusions
- NLR is a valuable and independent prognostic indicator for patients with renal cell carcinoma.
- Findings support the use of NLR in clinical decision-making for RCC patient management and treatment strategies.
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