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Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility:
Louise O Downs1,2, Dorcas Okanda2, Oscar Chirro2
1Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Open Forum Infectious Diseases
|March 21, 2025
Abstract:
We undertook a point-of-care test for hepatitis B core-related antigen in adults with hepatitis B virus in Kilifi, Kenya. A positive test identified all individuals with a hepatitis B viral load >200 000 IU/mL and who were hepatitis B e antigen positive. It also correlated with a higher alanine aminotransferase (ALT) level (P = .03), raised aspartate transaminase-to-platelet ratio index (APRI) (P < .001), and higher elastography scores (P = .03).

