Related Experiment Video
Updated: May 21, 2025
Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Bibliometric analysis of Crohn's disease in children, 2014-2024
Yanjing Zhu1,2, Yunhong Ma3, Zhengjiu Cui4
1The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Insights
Pediatric Crohn's disease research is increasing, with the United States leading publications. This bibliometric analysis visualizes trends and key contributors in pediatric Crohn's disease literature to aid future diagnosis and treatment.
Area of Science:
- Pediatric Gastroenterology
- Inflammatory Bowel Diseases
- Bibliometric Analysis
Background:
- Crohn's disease incidence is rising in children, impacting their health and families.
- Extensive research exists, but bibliometric analyses using visualization methods are lacking.
- This study addresses the need for a statistical overview of pediatric Crohn's disease literature.
Purpose of the Study:
- To statistically analyze published literature on pediatric Crohn's disease.
- To identify key authors, countries, institutions, and journals in the field.
- To provide a visual summary to support future diagnosis and treatment.
Main Methods:
- Screened literature from Web of Science Core Collection.
- Utilized Citespace (6.2.R4) and VOSviewer (1.6.18) for visualization and analysis.
- Analyzed authors, countries, institutions, journals, references, and keywords.
Main Results:
- Included 3,177 publications, showing an increasing trend.
- Dan Turner published most (78 articles); A. Levine was most cited author.
- United States and Tel Aviv University led in publications; Journal of Pediatric Gastroenterology and Nutrition published most.
- Key documents included ESPGHAN Revised Porto Criteria and ECCO-ESPGHAN Guideline Update.
- "Inflammatory bowel disease" was the most frequent keyword.
Conclusions:
- Provides a visual summary of pediatric Crohn's disease research.
- Highlights key contributors and trends in the field.
- Aims to foster international collaboration and advance research in pediatric Crohn's disease.
Background:
In recent years, the incidence of Crohn's disease has risen significantly in the pediatric population, and its prolongation has had a major impact on children's physical and mental health as well as on the quality of life of their families, and has therefore received extensive attention from scholars around the world. A large number of articles have been published on Crohn's disease in children; however, there is still a lack of studies that use visualization methods for bibliometric analysis of relevant literature. The purpose of this paper is to statistically analyze the published literature in the field of Crohn's disease in children in order to help in the future diagnosis and treatment of Crohn's disease in children.
Methods:
Literature meeting the inclusion criteria was screened from the Web of Science Core Collection database. Literature was visualized and analyzed by author, country, institution, journal, reference, and keyword using Citespace (6.2.R4) and VOSviewer (1.6.18).
Results:
A total of 3,177 eligible publications were included. There is an overall increasing trend in the number of annual publications.Turner, Dan published the most number of articles with 78 and has a high impact in the field of CD. The most cited author was Levine, A. Among countries and institutions, the United States and Tel Aviv University had the highest number of publications. The journal with the most publications is Journal Of Pediatric Gastroenterology And Nutrition. The most co-cited journal was Inflammatory Bowel Diseases. The most cited document was ESPGHAN Revised Porto Criteria for the Diagnosis of Inflammatory Bowel Disease in Children and Adolescents, and the most cited document with the highest outbreak intensity was The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.The most frequent keyword was "inflammatory bowel disease".
Conclusion:
This study provides a visual summary of information for the field of pediatric Crohn's disease and contributes to international collaboration to promote research in the field of pediatric Crohn's disease.
Related Concept Videos
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
01:24Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
01:29Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
01:21Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...