Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

127
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
127
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

127
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
127

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Side-locked Headache Associated with Habitual Neck-Shoulder Mobile Phone Clamping: A Case Series.

Annals of Indian Academy of Neurology·2026
Same author

Selective association and familial aggregation of migraine in epilepsy: evidence from a dual-control study.

Epilepsy & behavior : E&B·2026
Same author

Global, regional, and national burden of headache disorders, 1990-2021, with forecasts to 2050: A Global Burden of Disease study 2021.

Cell reports. Medicine·2025
Same author

Medication-overuse headache overlapping with serotonin syndrome.

Drug and therapeutics bulletin·2024
Same author

Serotonin syndrome controversies: A need for consensus.

World journal of critical care medicine·2024
Same author

Idiopathic Serotonin Syndrome - Does It Exist?

Annals of Indian Academy of Neurology·2024
Same journal

Long-term neurological consequences of hypertensive disorders of pregnancy: Implications for postpartum monitoring and intervention.

World journal of methodology·2026
Same journal

Comparative effectiveness of parenteral anticoagulants (fondaparinux, argatroban, bivalirudin) in heparin-induced thrombocytopenia: A systematic review.

World journal of methodology·2026
Same journal

Biases of large language models in diagnosing Cushing's syndrome.

World journal of methodology·2026
Same journal

Effects of spinal cord transcutaneous stimulation priming on single-leg balance control.

World journal of methodology·2026
Same journal

Why does hepatitis B remain underprioritized? A view through lived experience.

World journal of methodology·2026
Same journal

Improving diagnostic accuracy of 72-hour supervised fasting test for hypoglycemia evaluation: A quality improvement project.

World journal of methodology·2026
See all related articles

Related Experiment Video

Updated: May 21, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

17.9K

Restless head syndrome: A retrospective study.

Sanjay Prakash1, Varoon Vadodaria2, Niraj Chawda3

  • 1Department of Neurology, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth, Vadodara 391760, Gujarāt, India. drprakashs@yahoo.co.in.

World Journal of Methodology
|March 21, 2025
PubMed
Summary
This summary is machine-generated.

Restless legs syndrome (RLS) can affect the head, often presenting as headache or dizziness. Prompt diagnosis and treatment with dopaminergic medications are effective for this RLS variant.

Keywords:
DopamineHeadacheMigraineRestless head syndromeRestless legs syndromeTension-type headache

More Related Videos

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data
06:14

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

6.3K
An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.7K

Related Experiment Videos

Last Updated: May 21, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

17.9K
In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data
06:14

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

6.3K
An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
07:02

An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System

Published on: January 12, 2011

15.7K

Area of Science:

  • Neurology
  • Sleep Medicine

Background:

  • Restless legs syndrome (RLS) typically involves lower limb discomfort but can manifest in other body regions, including the head.
  • Reports of head-specific RLS symptoms are rare, necessitating further investigation.

Purpose of the Study:

  • To investigate the epidemiological and clinical characteristics of the head-variant of Restless Legs Syndrome (RLS).
  • To understand the presentation and treatment response of RLS affecting the head.

Main Methods:

  • A retrospective study of 17 adult patients diagnosed with RLS and experiencing concurrent head symptoms.
  • Analysis of patient demographics, symptom presentation, comorbidities, and treatment outcomes.

Main Results:

  • The median age of symptom onset was 41.6 years, with a near-equal male-to-female ratio.
  • Headache (70.5%) and dizziness (29.4%) were the most common presenting symptoms in the head, alongside typical RLS leg sensations.
  • Insomnia was a frequent comorbidity (88.2%), and all patients showed positive response to dopaminergic medications.

Conclusions:

  • Head RLS symptoms may be misdiagnosed as primary headache, dizziness, or psychosomatic disorders.
  • Head and leg symptoms in RLS could represent different clinical expressions of the same underlying condition.
  • Dopaminergic therapy is effective for head-involved RLS, suggesting a shared pathophysiology with typical RLS.