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Updated: May 21, 2025

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
Published on: January 7, 2014
Contributors to Gender Disparities in Parkinson's Disease Caregiving
Sarah Horn1, Yunfeng Dai2, Samuel S Wu2
1Department of Neurology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Abstract:
BackgroundWomen with Parkinson's disease (PD) are less likely to have a caregiver.ObjectiveTo determine factors contributing to gender disparities in PD caregiving.MethodsWe conducted a cross-sectional survey of people with PD and caregivers participating in the Parkinson's Foundation Parkinson's Outcomes Project and compared patient and caregiver characteristics by gender.ResultsAmong PD patients, 20.7% of 1663 women and 14.2% of 3005 men had no caregiver (P < 0.001). Women without caregivers were older (69.1 vs 66.3, P < 0.001), less likely to be married (30.4% vs 54.7%, P < 0.001), and more likely to be taking an antidepressant (41.8% vs 30.9%, P = 0.002) than men. Using stepwise logistic regression models, gender differences in access to caregiving were explained by marital status. Among caregivers, women reported more strain (P < 0.001) and had less time for other family members (P < 0.001).ConclusionFewer women with PD have caregivers because they are less likely to have a spouse.
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