Related Experiment Video
Updated: May 21, 2025

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Observational protocol on neuropsychological disorders in cardiovascular disease for holistic prevention and
Irene Cappadona1, Augusto Ielo1, Maria Pagano1
1Piemonte Hospital, IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
Insights
This study explores the links between cardiovascular disease (CVD) and cognitive issues, mental health, and associated disorders. Psychoeducational interventions show promise for improving patient well-being.
Area of Science:
- Integrative medicine
- Cardiology
- Neurology
- Psychiatry
Background:
- Cardiovascular disease (CVD) is a major global health concern.
- A holistic approach is crucial for assessing patients due to interconnected bodily functions.
- Existing research often overlooks the multifaceted impact of CVD on patients and their caregivers.
Purpose of the Study:
- To investigate the relationship between CVD and cognitive deficits.
- To assess the prevalence of anxiety, depression, and associated disorders (dysphagia, respiratory/sleep issues) in CVD patients.
- To evaluate the impact of CVD on caregivers and the effectiveness of psychoeducational interventions on patient well-being.
Main Methods:
- A cohort of at least 218 patients with CVD will be assessed at baseline (T0) and after 6 months (T1).
- Standardized neuropsychological, psychological, and clinical assessments will be employed.
- A psychoeducational intervention will be administered, with its effectiveness evaluated at T1.
Main Results:
- Comprehensive assessment identifies comorbidities and their impact.
- Psychoeducational intervention aims to improve overall patient well-being.
- The study seeks to identify risk factors and inform treatment strategies for CVD complications.
Conclusions:
- A holistic, multi-faceted approach is essential for understanding and managing CVD.
- Psychoeducation may offer a viable strategy for enhancing the well-being of patients with CVD and their caregivers.
- This research contributes to personalized treatment and prevention of future CVD-related complications.
Abstract:
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. In view of the close correlation between the functions of the body, which cannot be examined in a piecemeal manner but as an integrated system, a holistic approach allows for a comprehensive assessment of the patient. Our study aims to (i) examine the connection between CVD and cognitive deficits; (ii) examine the presence of anxiety and depression; (iii) evaluate the presence of dysphagia, pneumophonic coordination disorders, respiratory and sleep disorders; (iv) analyze the impact of CVD on the caregiver; and (v) evaluate the effectiveness of psychoeducational intervention. At least 218 patients will participate in the survey. At T0, they will undergo neuropsychological, psychological and associated clinical condition assessment through standardized tests. In addition, at least one psychoeducation meeting will be held. After 6 months (T1), the same tests will be repeated, and the effectiveness of psychoeducation will be evaluated. Assessment of associated disorders will provide a comprehensive view of the patient. In addition, it will be observed how psychoeducational intervention can make changes on general well-being. Comprehensive, multi-step observation allows for identification of risk factors, tailoring of treatment, and prevention of future complications.Clinical Trial Registration: registered on Clinicaltrials.gov (ID: NCT06413823).
Related Concept Videos
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Pre-Procedural Guidelines for Assessing Blood Pressure

