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Updated: May 21, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
The Acceptable Haemoglobin's Drop after Uncomplicated Caesarean Sections
Basel M Khreisat1, Ainur Donayeva2, Zainab Abdul Ameer Jaafar3
1Department of Obstetrics and Gynecology, King Hussain Medical Center, Royal Medical Services, Amman, Jordan.
Background:
Routine haemoglobin assay is a common postoperative (PO) practice after caesarean sections (CSs). There is no consensus regarding the acceptable haemoglobin's (Hb's) drop after uncomplicated CSs. Objective: To detect the acceptable Hb's drop after uncomplicated caesarean sections (CSs).
Material And Methods:
Seventy-five (75) participants delivered by uncomplicated elective CSs (ECSs) were recruited for the current study. Participants' pre-operative Hb was compared to PO-Hbs using t-test to detect the acceptable Hb's drop after uncomplicated ECSs. Correlations between the 48-hrs. PO-Hb's drop or 1-week PO-Hb's drop and estimated blood loss (EBL) during uncomplicated ECSs was detected using Pearson's correlation.
Results:
Mean duration of uncomplicated ECS was 43.3 ± 1.7 min. and mean EBL during uncomplicated ECSs was 654.4 ± 54.49 ml. No significant difference was detected in this study when 48-hrs. PO-Hb (10.89 ± 0.43 gms%) or 1-week PO-Hb (10.86 ± 0.46 gms%) were compared to the participants' pre-operative Hb (12.2 ± 0.46 gms%), (p=0.3 and 0.5, respectively). Mean 48-hrs. and 1-week PO-Hb's drop after uncomplicated ECSs were 1.28 ± 0.09 and 1.3 ± 0.07 gms%, respectively. The correlation between 48-hrs. PO-Hb's drop and EBL during uncomplicated ECSs was not significant (r=-0.14; p=0.23). The correlation between 1-week PO-Hb's drop and EBL during uncomplicated ECSs was also not significant (r=0.017; p=0.89).
Conclusions:
Mean 48-hrs. and 1-week PO-Hb's drop after uncomplicated ECSs were 1.28 ± 0.09 and 1.3 ± 0.07 gms%, respectively. Correlations between either the 48-hrs. PO-Hb's drop or 1-week PO-Hb's drop and EBL during uncomplicated ECSs were not significant.
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