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Updated: May 21, 2025

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
Published on: June 14, 2024
[Pathophysiology of neuromuscular weakness acquired in intensive care during sepsis]
Pauline Michel-Flutot1, Stéphane Vinit2, Arnaud Mansart3
1Department of Neuroscience, Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, États-Unis.
Abstract:
Sepsis is a potentially life-threatening condition recognized as a global health priority by the World Health Organization. Survivors who develop intensive care unit-acquired weakness (ICUAW) often face long-term motor and functional deficits that significantly impact their quality of life. Although some studies have investigated the mechanisms underlying ICUAW and its long-term effects, much remains unknown. Further research into ICUAW is therefore essential to gain a comprehensive understanding of this phenomenon, which may guide the development of effective treatments to restore patients' quality of life.
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