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Iatrogenic cyanoacrylate glue-induced eye injuries in the pediatric population: A national multicenter retrospective
A Mathieu1, , V Coste-Verdier1
1Service d'ophtalmologie, centre hospitalier universitaire de Bordeaux, 33000 Bordeaux, France.
Insights
Iatrogenic cyanoacrylate glue in pediatric eyes often causes mild symptoms like eyelid swelling and keratitis. Conservative management is preferred and generally leads to good outcomes without severe complications.
Area of Science:
- Ophthalmology
- Pediatric Emergency Medicine
- Toxicology
Background:
- Cyanoacrylate adhesives are widely used medically.
- Pediatric eye injuries from accidental glue spillage are common.
- Standardized management protocols are lacking for these incidents.
Purpose of the Study:
- To review the management and outcomes of pediatric ocular cyanoacrylate glue exposure.
- To identify common symptoms and complications.
- To evaluate the effectiveness of different treatment approaches.
Main Methods:
- Retrospective multicenter study utilizing French national adverse event data (1999-2023).
- Inclusion criteria: ocular cyanoacrylate exposure, closed eyelids, and age under 15.
- Analysis of symptoms, severity (Poisoning Severity Score), and treatment outcomes.
Main Results:
- Twenty pediatric cases were analyzed.
- Common symptoms included eyelid swelling (35%), superficial keratitis (20%), and conjunctivitis (20%).
- No severe ocular lesions were reported; spontaneous eyelid detachment averaged 8.5 days. Surgical interventions showed limited benefit.
Conclusions:
- Conservative management is the prevalent approach for pediatric ocular cyanoacrylate glue exposure in France.
- The study found no severe complications associated with these injuries.
- Current practices suggest a favorable prognosis with non-invasive treatments.
Introduction:
Cyanoacrylate adhesives serve multiple purposes and have increasingly been used in medical settings. Among pediatric emergencies, iatrogenic cyanoacrylate glue spillage into children's eyes is a common occurrence lacking standardized management recommendations.
Methods:
This retrospective multicenter study used the French national adverse event data from January 1, 1999, to July 1, 2023. Inclusion criteria included ocular cyanoacrylate glue exposure, closed eyelids, and age<15 years.
Results:
Among 20 pediatric patients studied, primary symptoms post-eyelid opening included eyelid swelling (35%), superficial keratitis (20%), and conjunctivitis (20%). Severity assessments using the Poisoning Severity Score (PSS) showed an absence of severe eye lesions. Spontaneous eyelid detachment took an average of 8.5 days. Surgical interventions in three cases exhibited limited improvement and potential iatrogenicity.
Conclusion:
This study indicates a prevalent preference for conservative management approaches to iatrogenic cyanoacrylate glue spills in pediatric ocular cases in France. No severe complications were reported among observed cases.
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