A prospective multicenter non-inferiority trial to evaluate a new burn rehabilitation program based on the...

Burn injuries have a lasting impact on physical and psychological health. This study evaluated outcomes for two burn-specific rehabilitation programs based on the International Classification of Functioning, Disability, and Health (ICF) model.

In a prospective multicenter trial, 103 patients with work-related burn injuries underwent multidisciplinary rehabilitation in either a newly established ICF-based program (Center A) or a well-established program (Center B). A comprehensive outcome assessment was performed at the beginning (T1) and the end of inpatient rehabilitation (T2), and at three (T3) and 12 months (T4) after discharge to evaluate the effectiveness of the two rehabilitation programs. The study included an analysis of longitudinal changes within each center to assess patient outcomes over time and a comparison between the two centers at each time point to evaluate potential differences in rehabilitation effectiveness. Primary outcomes were the Physical Component Score (PCS) and Mental Component Score (MCS) of the 36-Item Short Form Survey (SF-36), with secondary outcomes including grip strength, active range of motion (AROM), and burn scar assessment among others.

Results showed significant improvements in physical health (SF-36 PCS) from T1 to T4 (p < 0.001), while mental health (SF-36 MCS) showed no significant change (p = 0.20). Grip strength and AROM improved significantly over time in both centers. Non-inferiority between centers was confirmed for all outcomes except MCS at T2 and T3.

This study highlights the positive impact of ICF-based rehabilitation on physical recovery, with ongoing mental health needs underscoring the importance of long-term psychological support for burn survivors.