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Updated: Aug 10, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
Published on: June 11, 2015
Proteome-wide discovery of phage anti-defense proteins by Alphafold2
Zhifu Han1, Yu Cao1, Jijie Chai1
1Research Center for Industries of the Future, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake Laboratory of Life Sciences and Biomedicine, Westlake University, Hangzhou, Zhejiang 310024, China.
Abstract:
In a recent Cell study, Yirmiya et al.,1 using AlphaFold2-Multimer co-folding analyses, identify multiple phage inhibitors of bacterial defense systems on a proteome-wide scale and uncover a novel inhibition mechanism of these anti-defense proteins. The study significantly promotes our understanding of phage-bacteria interactions.
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