Neutering pathogens through green synthesized nanoparticles.

Area of Science:

• Veterinary Medicine
• Nanotechnology
• Antimicrobial Resistance

Background:

• Multidrug-resistant (MDR) pathogens in animals present a significant threat to veterinary care and public health.
• Conventional antimicrobial treatments are losing efficacy, driving the need for alternative therapeutic strategies.
• Plant-based nanoparticles (NPs) are emerging as a promising, low-toxicity approach to combat MDR pathogens.

Purpose of the Study:

• To explore the potential of plant-based nanoparticles as a novel strategy against MDR pathogens in animal diseases.
• To review the mechanisms of action, green synthesis methods, and veterinary applications of these nanoparticles.

Main Methods:

• Green synthesis of nanoparticles using plant-derived phytochemicals as reducing and stabilizing agents.
• Characterization of nanoparticle physicochemical properties (size, shape, surface characteristics) for enhanced antimicrobial activity.
• Review of existing literature on the efficacy and applications of plant-based NPs in veterinary medicine.

Main Results:

• Plant-based NPs demonstrate potent antimicrobial properties against MDR pathogens.
• Green synthesis offers an eco-friendly, cost-effective, and biocompatible method for NP production.
• Tunable physicochemical properties allow for optimization of antimicrobial potency and targeted action.

Conclusions:

• Plant-based nanoparticles represent a groundbreaking strategy to address MDR pathogens in veterinary medicine.
• Further research optimizing synthesis, assessing toxicity, and evaluating in vivo efficacy is crucial.
• These NPs hold significant potential as a tool against antimicrobial resistance (AMR) in animals, impacting global health.