Successful Balloon Atrial Septostomy in a Premature Infant.
Soujanya Bogarapu1, Ty E Hasselman1, Subhrajit Lahiri1
1Department of Pediatrics Cardiology, Division of Pediatrics, University of Illinois College of Medicine, Peoria, Illinois, USA.
JACC. Case Reports
|March 21, 2025
Summary
Balloon atrial septostomy (BAS) is a critical procedure for neonates with dextrotransposition of the great arteries (d-TGA). This case demonstrates a successful BAS in a very low-birthweight, premature infant, expanding its potential application.
Area of Science:
- Neonatal cardiology
- Pediatric cardiac surgery
- Interventional cardiology
Background:
- Balloon atrial septostomy (BAS) is a well-established palliative procedure for neonates diagnosed with dextrotransposition of the great arteries (d-TGA).
- The efficacy and safety of BAS in extremely premature or low-birthweight infants remain less understood due to their unique physiological challenges.
Observation:
- This report details a case involving a 2-day-old infant weighing 1.4 kg, born at 30 weeks gestation, who presented with d-TGA and a restrictive interatrial septum.
- The infant required immediate intervention to improve interatrial mixing and systemic oxygenation.
Findings:
- A successful balloon atrial septostomy was performed in this extremely low-birthweight, premature neonate with d-TGA.
- The procedure effectively created adequate atrial communication, leading to improved hemodynamics.
Implications:
- This successful case suggests that BAS can be a viable and life-saving option for very low-birthweight and premature infants with d-TGA.
- Further research and case series are warranted to establish standardized protocols for BAS in this vulnerable population.
- Expanding the application of BAS in high-risk neonates can improve outcomes for complex congenital heart disease.


