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Investigating the prevalence of the G2019S mutation in Parkinson's disease among a Libyan population
Nuri H Awayn1, Sara A Hashish2, Sultan A Salem3
1Department of Chemistry, Faculty of Sciences, University of Tripoli, Tripoli, Libya.
Abstract:
Parkinson's disease (PD) is a progressive neurodegenerative disorder influenced by both environmental and genetic risk factors. This study investigates the prevalence of the LRRK2 G2019S mutation in a Libyan population of 140 PD patients and 58 controls. Genetic analysis of blood samples revealed that 19.5% of PD patients carry the G2019S mutation, indicating a genetic association with the disease. The study highlights the G2019S mutation as a potential genetic risk factor for PD in Libya and emphasizes the importance of genetic screening for better understanding and management of the disease.
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