Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spatial light modulator via optically addressed metasurface.

Nature nanotechnology·2026

Same author

Light-driven lattice soft microrobot with multimodal locomotion.

Nature communications·2025

Same author

From fish to fiber: 3D-nanoprinted optical neuromast for multi-integrated underwater detection.

Nature communications·2025

Same author

Sericin-Based 3D High-Precision Biomimetic Microscaffold Fabricated by Laser Direct Writing for Tissue Engineering.

Nano letters·2025

Same author

3D Nanoprinting of Heterogeneous Metal Oxides with High Shape Fidelity.

Advanced materials (Deerfield Beach, Fla.)·2024

Same author

3D Directional Assembly of Liquid Crystal Molecules.

Advanced materials (Deerfield Beach, Fla.)·2024

Search research articles

Related Experiment Video

Updated: Apr 13, 2026

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

Bioinspired 3D-Nanoprinted Optical Sensilla for Bidirectional Respiratory Monitoring.

Liangye Li¹, Xuhao Fan², Wangyang Xu¹

¹Huazhong University of Science and Technology, School of Optical and Electronic Information, National Engineering Research Center for Next Generation Internet Access System (NGIA), Wuhan 430074, Hubei, China.

|March 22, 2025

Summary

A novel optical fiber sensor inspired by bat wings detects both inhalation and exhalation airflow. This breakthrough offers a stable, noninvasive tool for monitoring chronic respiratory diseases and improving patient outcomes.

Keywords:

All-optical fiber sensilla Bidirectional respiratory monitoring Bioinspired hair-like structure Chronic respiratory diseases Femtosecond laser 3D nanoprinting

More Related Videos

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

Related Experiment Videos

Last Updated: Apr 13, 2026

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

Area of Science:

Biomedical Engineering
Optical Sensing
Respiratory Medicine

Background:

Chronic respiratory diseases (CRDs) are a major global health concern.
Current airflow sensors lack stability and directional differentiation (inhalation/exhalation).
Effective monitoring is vital for CRD management and patient outcomes.

Purpose of the Study:

To develop a novel all-optical fiber sensor for bidirectional airflow detection.
To overcome limitations of existing respiratory monitoring technologies.
To provide a precise, noninvasive tool for CRD assessment.

Main Methods:

Utilized femtosecond laser 3D nanoprinting to integrate optical Merkel cells and microhairs at a fiber tip.
Mimicked bat-wing hair structures for airflow interaction.
Monitored spectral drift in optical Merkel cells caused by nanoscale deformations due to airflow.

Main Results:

Achieved bidirectional airflow detection with high sensitivities (19.16 nm/(L/min) and -24.46 nm/(L/min)).
Demonstrated record-high sensor stability over 10,000 cycles.
Successfully identified respiratory patterns, distress signals, and apnea signs.

Conclusions:

The developed optical fiber sensilla is a highly stable and sensitive bidirectional airflow sensor.
The ultracompact design facilitates integration into medical devices like masks or endotracheal tubes.
This technology offers a promising noninvasive solution for CRD monitoring and emergency response.