AGA Living Clinical Practice Guideline on Computer-Aided Detection-Assisted Colonoscopy

Area of Science:

• Gastroenterology
• Medical Technology
• Artificial Intelligence

Background:

• American Gastroenterological Association (AGA) guideline on computer-aided detection (CADe) systems.
• Focus on CADe for colorectal polyp detection during colonoscopy.

Purpose of the Study:

• Provide evidence overview for endoscopists and patients.
• Support decision-making regarding CADe use in colonoscopy.

Main Methods:

• Multidisciplinary panel using GRADE framework.
• Systematic reviews on CADe effects, patient values, and AI trust.
• Microsimulation study on long-term outcomes.

Main Results:

• No recommendation for or against CADe due to very low certainty of evidence.
• Acknowledged 8% increase in adenoma detection rate.
• Noted potential for increased surveillance burden and cost implications.

Conclusions:

• Close tradeoff between benefits and harms of CADe.
• Current evidence limitations hinder a definitive recommendation.
• Ongoing research and AI iteration may inform future guidelines.