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Updated: May 21, 2025

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
Open-transmit and flexible receiver array for high resolution ultrahigh-field fMRI of the human sensorimotor cortex
Zidong Wei1,2,3,4, Zhilin Zhang5, Qiaoyan Chen1,3
1Lauterbur Imaging Research Center, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Abstract:
In this study, we developed an open-transmit and 24-channel flexible receiver head coil assembly tailored for high-resolution ultrahigh-field functional magnetic resonance imaging (fMRI) of the human somatosensory and motor cortex. Leveraging the increased signal-to-noise ratio (SNR) and spatial resolution of ultrahigh field MRI, we address the technical challenges inherent in fMRI coil design. The open-birdcage transmit coil enhances patient comfort and enables visual task implementation, demonstrating superior performance in transmit efficiency and specific absorption rate distribution compared to conventional coils. Furthermore, the 24-channel flexible receiver head coil offers enhanced SNR and image quality, facilitating sub-millimeter vascular-space-occupancy imaging for precise functional mapping. These advancements provide valuable tools for unraveling the intricacies of somatosensory and motor cortex function. By enriching human brain functional studies, they contribute significantly to our understanding of the mechanisms underlying somatosensory and motor cortex function and may have valuable clinical applications in neurology and neuroscience research.

