Viviparity and obligate blood feeding: tsetse flies as a unique research system to study climate change

Tsetse flies (Glossina species) are unique organisms that combine several remarkable traits: they are obligate blood feeders, serve as critical vectors for African trypanosomes, and reproduce through adenotrophic viviparity - a process in which offspring are nourished with milk-like secretions before being born live. Here, we explore how climate change will impact the physiological processes associated with live birth in tsetse. This includes considerations of how blood feeding, host-pathogen interactions, and host-symbiont dynamics are likely to be impacted by thermal shifts. The highly specialized biology of tsetse flies suggests that this system is likely to have a distinctive response to climate change. Thus, detailed empirical research into these unique features is paramount for predicting tsetse population dynamics under climate change, with caution required when generalizing from other well-studied vectors with contrasting ecology and life histories such as mosquitoes and ticks. At the same time, the reproductive biology of tsetse, as well as microbiome and feeding dynamics, allow for a powerful model to investigate climate change through the lens of pregnancy and associated physiological adaptations in an extensively researched invertebrate.