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2025 Consensus on the Clinical Pathway of Blood Cholesterol Management in Taiwan
Yi-Heng Li1, Chung-Liang Shih2
1Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan.
Insights
Achieving cholesterol targets remains a challenge for atherosclerotic cardiovascular disease (ASCVD) prevention in Taiwan. This clinical pathway aims to improve low-density lipoprotein cholesterol (LDL-C) management and patient outcomes.
Area of Science:
- Cardiology
- Metabolic Disorders
- Public Health
Background:
- Elevated low-density lipoprotein cholesterol (LDL-C) is a primary risk factor for atherosclerotic cardiovascular disease (ASCVD).
- Suboptimal achievement of recommended LDL-C targets necessitates improved management strategies in Taiwan.
- There is a significant need to enhance lipid control for individuals at risk of or with ASCVD.
Purpose of the Study:
- To introduce a clinical pathway for optimizing cholesterol management in Taiwan.
- To improve clinical outcomes for ASCVD patients through effective lipid control.
- To facilitate the achievement of individualized LDL-C targets and reduce cardiovascular events.
Main Methods:
- Development of a clinical pathway based on Taiwan lipid guidelines and expert consensus.
- Proposal of tailored LDL-C targets for varying ASCVD risk levels.
- Standardization of lipid management and follow-up protocols for patients on lipid-lowering therapy.
Main Results:
- The pathway provides clear LDL-C targets for different ASCVD risk strata.
- It standardizes the approach to lipid management and patient monitoring.
- Aims to optimize lipid-lowering therapy for better patient adherence and efficacy.
Conclusions:
- The clinical pathway offers a structured approach to enhance LDL-C target attainment in Taiwan.
- It is designed to improve monitoring and optimization of lipid-lowering therapies.
- Ultimately, it seeks to reduce the incidence of ASCVD events through better cholesterol management.
Abstract:
Increased low-density lipoprotein cholesterol (LDL-C) is one of the most important risk factors for atherosclerotic cardiovascular disease (ASCVD). However, the attainment rate of recommended LDL-C targets is not optimal with significant scope for improvement in Taiwan. This clinical pathway for cholesterol management was developed based on the Taiwan lipid guidelines and expert opinions from major medical societies in Taiwan. It was designed with the aim of improving the outcomes of people at risk of or with ASCVD who would benefit from lipid control to reduce the risk of new or recurrent cardiac events. The pathway proposes adequate LDL-C targets for people at different risk levels of ASCVD and standardizes lipid management and follow-up in patients receiving lipid lowering therapy. The ultimate purpose is to facilitate the attainment of individual LDL-C targets and ensure that patients are monitored adequately and optimized on the appropriate lipid lowering therapy to reduce the risk of ASCVD.
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