Rhabdomyolysis, acute renal failure, and disseminated intravascular coagulation in a man with sickle cell trait

We have described a patient with sickle cell trait who, after severe exertion, had rhabdomyolysis, acute renal failure, and disseminated intravascular coagulation secondary to sickling. Autopsy showed the characteristic histopathology of sickle cell crisis and not terminal sicklemia.