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Pheochromocytoma presenting with chest pain, heart failure and elevated pancreatic enzymes

Qinglang Li1,2, Shiyao Cheng1,2, Zhichong Chen1,2

  • 1Department of Cardiology, The Sixth Affiliated Hospital, Sun Yat-sen University, 26 Yuancun Erheng Road, Guangzhou 510655, China.

Oxford Medical Case Reports
|March 24, 2025
PubMed

Insights

Pheochromocytoma, a rare adrenal tumor, can mimic heart attacks, leading to misdiagnosis. Early recognition of this condition is crucial for timely treatment and patient recovery.

Area of Science:

  • Endocrinology
  • Cardiology
  • Oncology

Background:

  • Pheochromocytoma is a rare neuroendocrine tumor of the adrenal medulla.
  • It can cause a wide range of symptoms, often mimicking other conditions.
  • Misdiagnosis can lead to delayed treatment and adverse outcomes.

Observation:

  • A patient presented with acute chest pain, de Winter electrocardiogram (ECG) changes, and elevated troponin I, initially suggesting acute myocardial infarction.
  • Coronary angiography showed no significant coronary artery stenosis.
  • The patient later developed heart failure symptoms and had elevated serum amylase, lipase, and catecholamines.

Findings:

  • Further investigations confirmed the diagnosis of pheochromocytoma.
  • The patient underwent successful tumor resection.
  • Post-operative recovery was uneventful.

Implications:

  • This case underscores the importance of considering pheochromocytoma in the differential diagnosis of acute coronary syndromes.
  • Prompt recognition and management of pheochromocytoma are vital for preventing severe cardiovascular complications.
  • Highlighting the atypical presentations of pheochromocytoma aids clinicians in improving diagnostic accuracy.

Keywords:
chest painheart failurehyperamylasemiahyperlipasemiapheochromocytoma

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