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Severe Invasive Pneumococcal Infection With Multiple Abscesses Caused by a Less Virulent Serotype 1 Pneumococcus: A

Takae Okuno1, Megumi Hamaguchi2, Amano Yoshihiro2

  • 1Department of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine, izumo, JPN.

Cureus
|March 24, 2025
PubMed

Insights

A rare, severe case of invasive pneumococcal disease caused by serotype 1 pneumococcus in an older adult highlights the importance of pneumococcal conjugate vaccine (PCV13) and pneumococcal polysaccharide vaccine (PPSV23).

Area of Science:

  • Infectious Diseases
  • Vaccinology
  • Clinical Case Reports

Background:

  • Invasive pneumococcal disease (IPD) severity varies by serotype.
  • Serotype 1 pneumococcus typically causes less severe disease, like empyema, with a low fatality rate.
  • IPD cases with systemic abscesses and sepsis are rarely reported for serotype 1.
Keywords:
case reportempyemainvasive pneumococcal diseasenon-vaccine serotypeserotype replacement

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